The Brazilian forward has scored two goals in three Champions League games this season, as well as five assists, and has four goals in eight appearances in La Liga.
Elsewhere Pep Guardiola has named both Sergio Aguero and Kevin de Bruyne in his starting lineup for the clash at the Etihad Stadium.
Aguero also has three goals in four games this season in the Champions League and seven in seven starts in the Premier League.
Barcelona won 4-0 in the reverse fixture at Camp Nou with former Barca and now-City goalkeeper Claudio Bravo seeing red.
Manchester City starting XI: Caballero; Zabaleta, Stones, Otamendi, Kolarov; Fernandinho, Gundogan; Silva, De Bruyne, Sterling; Aguero.
Barcelona starting XI: Ter Stegen; Digne, Umtiti, Mascherano, Roberto; Busquets, Andre Gomes, Rakitic; Messi, Suarez, Neymar